WHO interim recommendations for the protection of persons
involved in the mass slaughter of animals potentially infected with highly
pathogenic avian influenza viruses
(WHO Regional Office for the Western Pacific, Manila,
26 January 2004)
Avian influenza is a highly contagious disease of birds which is currently
epidemic amongst poultry in Asia. Exposure to infected poultry and their feces
or dust/soil contaminated with feces) can result in human infection. These
recommendations have been developed because human infections have been
identified in association with the current poultry epidemic. They will be
updated as more information becomes available.
- Cullers and transporters should be provided with appropriate personal
protective equipment:
- protective clothing, preferably coveralls plus an impermeable apron or
surgical gowns with long cuffed sleeves plus an impermeable apron;
- heavy duty rubber work gloves that may be disinfected
- N95 respirator masks are preferred1. Standard well-fitted
surgical masks should be used if N95 respirators are not available2
- goggles;
- rubber or polyurethane boots that can be disinfected or protective
foot covers that can be discarded
- All persons who have been in close contact with the infected animals
should wash their hands frequently with soap and water. Cullers and
transporters should disinfect their hands after the operation.
- Environmental clean up should be carried out in areas of culling, using
the same protective measures as above.
- All persons exposed to infected chickens or to farms under suspicion
should be under close monitoring by local health authorities.
- It is recommended that oseltamivir be readily available for the treatment
of suspected H5N1 respiratory infections in cullers and farm workers
involved in the mass culling3.
- They should also be vaccinated with the current WHO recommended influenza
vaccine to avoid simultaneous infection by human influenza and avian
influenza and to minimize the possibility of a re-assortment of the virus's
genes4.
- Additional health monitoring of chicken cullers, others involved in the
process and their family members should be carried out. These individuals
should report any relevant health problems (respiratory complaints, flu-like
illnesses or eye infections) to a health care facility. Persons at high risk
for severe complications of influenza (e.g. immunocompromised, over 60 years
old, or with known chronic heart or lung disease) should avoid working with
affected chickens.
- Serological surveillance of exposed animal workers and veterinarians is
encouraged.
- In liaison with designated laboratories, full blood and post mortem
specimens (intestinal contents, anal and oro-nasal swabs, trachea, lung,
intestine, spleen, kidney, brain, liver and heart) of animals (including
pigs) should be collected for investigation of new viral isolates.
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1 US NIOSH certified N-95,
European CE P2, or comparable national/regional standards applicable to the
country of manufacture. Higher level particulate respirators may also be used.
2 In the control of the outbreak of avian influenza in the
Netherlands in 2003, N95 or equivalent respiratory protection was used.
3 For treatment, oseltamivir phosphate (TamifluŽ): 75 mg capsule
twice daily, for 5 days.
4 All concerned (persons at risk both environmentally and
occupationally) should be vaccinated with the current WHO recommended influenza
vaccine as soon as possible prior to anticipated risk exposure (2 weeks are
required to develop preventive immunity by vaccination.). This does not
specifically protect against H5N1.
It is important that both the animal/agricultural and the human health
sectors work together to improve the implementation of the above measures.
The above measures may be revised if new information on the local situation
becomes available.
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Source: WHO web site (http://www.wpro.who.int/avian/docs/recommendations.asp)